Label-Free Technologies For Drug Discovery

By: Matthew Cooper (Editor), Lorenz M. Mayr (Editor)

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Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories.

"Label-Free Technologies For Drug Discovery" summarises the latest and emerging developments in label-free detection systems, their underlying technology principles and end-user case studies that reveal the power and limitations of label-free in all areas of drug discovery.

Label-free technologies discussed include SPR, NMR, high-throughput mass spectrometry, resonant waveguide plate-based screening, transmitted-light imaging, isothermal titration calorimetry, optical and impedance cell-based assays and other biophysical methods. The technologies are discussed in relation to their use as screening technologies, high-content technologies, hit finding and hit validation strategies, mode of action and ADME/T, access to difficult target classes, cell-based receptor/ligand interactions particularly orphan receptors, and antibody and small molecule affinity and kinetic analysis.

"Label-Free Technologies For Drug Discovery" is an essential guide to this emerging class of tools for researchers in drug discovery and development, particularly high-throughput screening and compound profiling teams, medicinal chemists, structural biologists, assay developers, ADME/T specialists, and others interested in biomolecular interaction analysis.

Title: Label-Free Technologies For Drug Discovery

Author Name: Matthew Cooper (Editor), Lorenz M. Mayr (Editor)

Categories: Other,

Publisher: U.S.A, Wiley: 2011

ISBN Number: 0470746831

ISBN Number 13: 9780470746837

Binding: Hard Cover

Book Condition: New

Seller ID: 066726

Description: New. Label-Free Technologies For Drug Discovery By Matthew Cooper (Editor), Lorenz M. Mayr (Editor) Product Details Hardcover: 348 pages Publisher: Wiley; 1 edition (March 14, 2011) Language: English ISBN-10: 0470746831 ISBN-13: 9780470746837 Product Dimensions: 6.4 x 0.9 x 9.2 inches

Keywords: Label-Free Technologies For Drug Discovery